Ultra-high-resolution brain MRI at 0.55T: bSTAR and its application to magnetization transfer ratio imaging.

ABSTRACT:

Purpose

This study aims to evaluate the feasibility of structural sub-millimeter isotropic brain MRI at 0.55 T using a 3D half-radial dual-echo balanced steady-state free precession sequence, termed bSTAR and to assess its potential for high-resolution magnetization transfer imaging.

Methods

Phantom and in-vivo imaging of three healthy volunteers was performed on a low-field 0.55 T MR-system with isotropic bSTAR resolution settings of 0.87 × 0.87 × 0.87 mm³ and 0.69 × 0.69 × 0.69 mm³. Furthermore, off-resonance mapping was performed using 3D double-echo spoiled gradient imaging. For magnetization transfer (MT) MRI, the RF pulse duration of the 0.87 mm bSTAR scan was modified. Data were reconstructed using a GPU-accelerated compressed sensing algorithm.

SUBMITTER: Bauman G 

PROVIDER: S-EPMC11910248 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature