Association between congenital Zika syndrome and hospitalizations during early childhood: a nationwide cohort study.

ABSTRACT:

Objectives

Congenital Zika Syndrome (CZS) has been linked to a wide spectrum of abnormalities. However, differences in hospitalization patterns between children with and without CZS have not yet been investigated.

Methods

We compared rates of hospital admissions for all and specific diseases, proportions of admission causes, and total length of hospital stay (LOS) between children with CZS and those without the syndrome. Adjusted incidence rate ratios (aIRR) and aLOS were estimated using negative binomial regression.

Results

Compared to those without CZS, the aIRR for all-cause hospitalizations in the CZS group ranged from 3.77 (95%CI: 3.47-4.06) in the neonatal period to 7.76 (95%CI: 6.91-8.61) at ages 2-4 years. Similar trends were observed for specific causes of ad

SUBMITTER: Tedde JGG 

PROVIDER: S-EPMC11910342 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature