Identification of Naegleria fowleri antigens recognized by serum antibodies from people of Mexicali Valley, Mexico.

ABSTRACT: Naegleria fowleri is an amoeba that causes a fatal disease in the central nervous system known as primary amoebic meningoencephalitis (PAM) in humans. Most of the infections are acquired by people who practice recreational activities in water contaminated with trophozoites. Swimming and wading in irrigation channels of Mexicali are common practices for local people. Although there are some warning signposts in the surrounding sites, people continue using these channels for recreational purposes. In that region, cases of PAM have been reported; however, not everyone who comes into contact with contaminated water containing trophozoites becomes infected, and the factors influencing their immune response to N. fowleri remain unknown. We analyzed the levels of antibodies against N. fowleri in

SUBMITTER: Rodriguez-Mera IB 

PROVIDER: S-EPMC11910403 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature