Melatonin-protein interactions are dependent on yeast carbon metabolism.

ABSTRACT: Melatonin is an indole amine that is synthesized and interacts with glycolytic proteins during alcoholic fermentation in Saccharomyces and non-Saccharomyces yeasts depending on their yeast fermentative capacity. Due to its importance as a bioactive compound and antioxidant molecule, the aim of this study was to analyse the intracellular melatonin profile and melatonin-protein interactions in a large number of wine yeast species during alcoholic fermentation and respiration to determine whether these interactions were related to a specific carbon metabolism. Melatonin concentrations were analysed by liquid chromatography‒mass spectrometry, and proteins bound to melatonin were immunopurified at different time points during yeast growth. Intracellular melatonin followed a similar pattern in a

SUBMITTER: Morcillo-Parra MA 

PROVIDER: S-EPMC11910637 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature