The overgrowth of structure-function coupling in premature brain during infancy.

ABSTRACT: Although the rapid growth of brain structure and function during infancy has been well documented, relatively little is known about how these two developmental processes couple-an aspect that exhibits distinct patterns in adult brain. In this study, the multimodal MRI data from the dHCP database were used to investigate the coupling between brain structure and function in infants, with a particular focus on how prematurity influences this relationship. A similar pattern of the coupling distribution between preterm and full-term infants was identified with coupling index varying across unimodal cortices such as visual and sensorimotor regions and transmodal cortices including default mode network. Notably, a widespread overgrowth of structure-function coupling and a slow developmental traje

SUBMITTER: Wang R 

PROVIDER: S-EPMC11910680 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature