Outcomes of Donation After Circulatory Death Heart Transplantation Using Normothermic Regional Perfusion.

ABSTRACT:

Background

Donation after circulatory death (DCD) with cardiopulmonary bypass for thoracoabdominal normothermic regional perfusion (TA-NRP) has led to increased use of donor hearts. Rejection rates and long-term survival outcomes are not known.

Methods

A single-center retrospective cohort review of patients who underwent DCD heart transplantation from January 2020 to December 2023 was performed. Donor and recipient characteristics, operative characteristics, and posttransplantation outcomes were analyzed. Subgroup analysis comparing co-localized vs distant donors and recipients was performed. The primary end point was 1-year survival. Secondary end points included incidences of primary graft dysfunction (PGD), cardiac allograft vasculopathy (CAV), rejection rate, and overall

SUBMITTER: Kumar A 

PROVIDER: S-EPMC11910781 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature