Multicenter cross-sectional study of HTLV-1 prevalence and associated risk factors in epidemiologically relevant groups across Brazil.

ABSTRACT:

Background

Human T cell lymphotropic virus type 1 (HTLV-1) is highly endemic in Brazil, necessitating surveillance studies to understand its epidemiology. While previous research has focused on either specific cities or populations, there is a need for multicenter studies encompassing epidemiologically relevant populations to ascertain more accurate prevalence rates and predictors of HTLV-1 infection in the country.

Methods

We conducted a multicenter, cross-sectional study involving 3,184 participants across seven cities and five study populations in Brazil. Blood samples were collected, and the prevalence of HTLV-1 infection was determined by enzyme-linked immunosorbent assay (ELISA) and Western blot. Binary logistic regression analysis was used to determine risk factors of

SUBMITTER: Brites C 

PROVIDER: S-EPMC11911192 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature