Thrombocytopenia following kidney transplantation: a frequent, underestimated and potentially severe complication.

ABSTRACT:

Introduction

Cytopenias occur frequently after kidney transplantation but posttransplantation thrombocytopenia (PTTCP) frequency has rarely been reported.

Methods

This monocenter, retrospective study aimed to describe PTTCP frequency, causes, treatments and outcomes. PTTCP was defined as thrombocytopenia with ≥2 platelet counts <100×10⁹/L after first month posttransplantation.

Results

Among 2118 kidney-transplant recipients between 2002 and 2018, 189 (8.9%) developed PTTCP. Their mean platelet-count nadir was 51×10⁹/L [range 4-96×10⁹]; nadir was <50×10⁹/L for 87 (46.0%) patients. Main identified PTTCP etiologies were drugs (24.3%), or infectious diseases (20.1%; cytomegalovirus causing 79.4% of them), or unknown for 26 (13.7

SUBMITTER: Leonard C 

PROVIDER: S-EPMC11911467 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature