Prognostic impact of iron deficiency in new-onset chronic heart failure: Danish Heart Failure Registry insights.

ABSTRACT:

Aims

Iron deficiency (ID) is prevalent in chronic heart failure (HF) but lacks a consensus definition. This study evaluates the prevalence and the prognostic impact of ID using different criteria on all-cause and cardiovascular mortality, as well as first hospitalization for HF in patients with new-onset chronic HF.

Methods

In this nationwide registry-based cohort, we explored four definitions of ID: the current European Society of Cardiology (ESC) guidelines [ferritin <100 ng/mL or ferritin 100-299 ng/mL and transferrin saturation (TSAT) <20%], ferritin level <100 ng/mL, TSAT < 20% and serum iron ≤13 μmol/L. Patients were identified through the Danish Heart Failure Registry.

Results

Of 9477 new-onset chronic HF patients registered in the Danish Heart Failure Registry

SUBMITTER: Mohamed AA 

PROVIDER: S-EPMC11911571 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature