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A contemporary simple risk score for prediction of severe acute kidney injury after heart transplantation.


ABSTRACT:

Background

The aim of this study was to develop a simple risk score to estimate severe acute kidney injury (AKI) risk based on a large contemporary heart transplantation (HT) cohort.

Methods

From 1 January 2015 to 31 December 2021, all consecutive HT recipients in our institute were included and analysed for the occurrence of AKI within the first seven postoperative days. Patients transplanted between 2015 and 2019 comprised the derivation cohort, and those transplanted between 2020 and 2021 formed the validation cohort. The primary endpoint was severe AKI (AKI stages 2-3). The impact of severe AKI on 90 day mortality was also evaluated.

Results

Overall, 430 HT patients were included in the derivation cohort, and 108 were included in the validation cohort. Postoperati

SUBMITTER: Zhu S 

PROVIDER: S-EPMC11911592 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature