Association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and metabolic dysfunction-associated steatotic liver disease.

ABSTRACT:

Background

Metabolic dysfunction-associated steatotic liver disease (MASLD) is one of the most widespread chronic liver diseases and a serious global public health problem. Further research to identify novel risk factors associated with MASLD is urgently needed. The non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) was identified as a novel lipid marker. The objective of this research was to assess the association between NHHR and MASLD in adults.

Methods

This cross-sectional study utilized data from the 2017-2020 National Health and Nutrition Examination Survey (NHANES). MASLD was diagnosed in accordance with controlled attenuation parameter scores and a combination of cardiometabolic risk factors. Multivariate logistic regression

SUBMITTER: Yang D 

PROVIDER: S-EPMC11912010 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature