The prognostic significance of fragile X mental retardation syndrome-related protein 1 (FXR1) in breast cancer.

ABSTRACT:

Background

Breast cancer (BC) is a highly heterogeneous disease with variable histological appearance, biological features, clinical outcomes, and treatment responses. The number of BC cases in Saudi Arabia has more than tripled during the last 17 years to constitute 30% of all cancer cases in women. Therefore, greater efforts are needed to evaluate prognostic factors for BC in Saudi Arabia to improve prognostication and provide more personalized therapy. Recently, fragile X mental retardation syndrome-related protein 1 (FXR1) was identified as a novel biomarker that contributes to oncogenesis; however, its role in BC has not been well studied. This study aims to evaluate the clinicopathological significance of FXR1 in women with primary BC.

Methods

The protein levels of FXR

SUBMITTER: Alsalmi OA 

PROVIDER: S-EPMC11912039 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature