Androgen receptor expression distribution characteristics in young female breast cancer patients in China: a study of clinicopathological features.

ABSTRACT:

Background

The expression of androgen receptor (AR) in breast cancer has potential implications for predicting clinical outcomes, especially amongst young female patients. Numerous studies have reported that the co-expression of AR with hormone receptors (HRs) is correlated with a favorable prognosis in breast cancer. However, research on the frequency and distribution of AR expression in Chinese breast cancer patients is limited. This study aims to investigate the relationship between AR expression and the expression of progesterone receptor (PR), estrogen receptor (ER), P53, human epidermal growth factor receptor 2 (HER2), and epidermal growth factor receptor (EGFR) in breast cancer patients, and the distribution of molecular subtypes of breast cancer. Further, we aim to explore

SUBMITTER: Tu J 

PROVIDER: S-EPMC11912052 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature