Comprehensive analysis of the immunological implication and prognostic value of MEAK7 in non-small cell lung cancer.

ABSTRACT:

Background

The mechanistic target of rapamycin (mTOR)-associated protein Eak-7 homolog (MEAK7) is widely involved in the occurrence and development of various diseases, including tumors. However, the role of MEAK7 in non-small cell lung cancer (NSCLC) and its underlying mechanism in the tumor microenvironment remain unclear. The purpose of this paper is to explore the role of MEAK7 in the prognosis of NSCLC.

Methods

The expression levels of MEAK7 were examined through the utilization of The Cancer Genome Atlas (TCGA) and the genotype-tissue expression project's pan-cancer dataset. Within this context, the relationships between MEAK7 expression and various clinical features, as well as patient outcomes, were assessed using a comprehensive array of bioinformatics

SUBMITTER: Miao JY 

PROVIDER: S-EPMC11912075 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature