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Diagnostic accuracy of pleural fluid carbohydrate antigen 72-4 for malignant pleural effusion: a systematic review and meta-analysis.


ABSTRACT:

Background

Several studies have evaluated the diagnostic accuracy of pleural fluid carbohydrate antigen 72-4 (CA72-4) for malignant pleural effusion (MPE), but the results were diverse. This systematic review and meta-analysis aimed to evaluate the diagnostic accuracy of pleural fluid CA72-4 for MPE.

Methods

The PubMed and Web of Science databases were searched to verify potential studies investigating the diagnostic accuracy of pleural fluid CA72-4 for MPE. The last search date was August 2024. The quality of the eligible studies was assessed by this study using the revised diagnostic accuracy study quality assessment tool-2 to assess the quality of the eligible studies. This study used a summary receiver operating characteristic (sROC) curve and a bivariate model to pool t

SUBMITTER: Cao XS 

PROVIDER: S-EPMC11912079 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature