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The screening of optimal primary tumor resection candidates in patients with small cell lung cancer: a population-based predictive model.


ABSTRACT:

Background

Although a strong survival benefit has been observed among small cell lung cancer (SCLC) patients undergoing surgery, not all SCLC patients benefit from surgery. To help clinicians make choices and decisions regarding surgical intervention, we have developed an effective model to screen beneficial candidates based on population and tumor characteristics.

Methods

Patients with SCLC were acquired from the Surveillance, Epidemiology, and End Results database. Propensity score matching (PSM) was performed to balance covariates between the surgery and non-surgery groups. We assumed that patients undergoing surgery between 2014 and 2018 would benefit from the procedure if their median cancer-specific survival (CSS) time was longer than that of non-surgical patients. Uni

SUBMITTER: Wang Z 

PROVIDER: S-EPMC11912087 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature