Spontaneous Formation of a Sustainable Antifreeze Coating by Peptide Self-Assembly.

ABSTRACT: The formation of ice and frost on surfaces poses significant challenges to aviation, crop protection, organ preservation, and other fields. This paper presents the formation of sustainable antifreeze coating by the self-assembly of short peptides. The peptide design is inspired by and combines different elements from distinct natural proteins: (i) a sequence of amino acids from an antifreeze protein and (ii) the amino acids 3,4-dihydroxyphenylalanine (DOPA) and lysine from mussel adhesion proteins that anchor the peptide to a surface. The peptide, termed AFPep1, incorporates the repetitive ice-binding motif found in the antifreeze protein of the longhorn beetle (Rhagium inquisitor). Surfaces coated with the peptide exhibited antifreeze activity with a delay of the initial freezing o

SUBMITTER: Kaganovich M 

PROVIDER: S-EPMC11912201 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature