Widespread impact of transposable elements on the evolution of post-transcriptional regulation in the cotton genus Gossypium.

ABSTRACT:

Background

Transposable element (TE) expansion has long been known to mediate genome evolution and phenotypic diversity in organisms, but its impact on the evolution of post-transcriptional regulation following species divergence remains unclear.

Results

To address this issue, we perform long-read direct RNA sequencing, polysome profiling sequencing, and small RNA sequencing in the cotton genus Gossypium, the species of which range more than three folds in genome size. We find that TE expansion contributes to the turnover of transcription splicing sites and regulatory sequences, leading to changes in alternative splicing patterns and the expression levels of orthologous genes. We also find that TE-derived upstream open reading frames and microRNAs serve as regulatory element

SUBMITTER: Tian X 

PROVIDER: S-EPMC11912738 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature