Body mass index across adulthood, weight gain and cancer risk: a population-based cohort study.

ABSTRACT:

Background

Although the association between excess weight and cancer risk is well established, it is not known how this association evolves across the lifespan. We aimed to investigate the strength of the association of excess weight at different ages in adulthood and adult weight gain with cancer risk.

Methods

We used data from a German population-based cohort study of 9,218 participants aged 50-75 (mean 62) years recruited between 2000 and 2002. Participants provided socio-demographic, medical, and lifestyle data, including self-reported current height and weight (at ages 20, 30, 40, 50 and baseline). Main exposures were body mass index (BMI, kg/m²) at different ages and weight change (kg) since age 20. The outcome was obesity-related cancer (13 types). Hazard r

SUBMITTER: Mandic M 

PROVIDER: S-EPMC11912780 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature