The Breeding Sex Ratio Interacts With Demographic History to Shape Comparative Patterns of Variation on the X Chromosome and the Autosomes.

ABSTRACT: In many populations, unequal numbers of females and males reproduce each generation. This imbalance in the breeding sex ratio shapes patterns of genetic variation on the sex chromosomes and the autosomes in distinct ways. Despite recognition of this phenomenon, effects of the breeding sex ratio on some aspects of variation remain unclear, especially for populations with nonequilibrium demographic histories. To address this gap in the field, we used coalescent simulations to examine relative patterns of variation at X-linked loci and autosomal loci in populations spanning the range of breeding sex ratio with historical changes in population size. Shifts in breeding sex ratio away from 1:1 reduce nucleotide diversity and the number of unique haplotypes and increase linkage disequilibrium and

SUBMITTER: Spurley WJ 

PROVIDER: S-EPMC11913216 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature