Evaluating the multifaceted bioactivity of <i>Syzygium aromaticum</i> essential oil: the central role of eugenol.

ABSTRACT:

Background/aim

Syzygium aromaticum L. is a versatile plant traditionally used to treat digestive and respiratory issues, improve oral health, and relieve pain, particularly in regions such as Southeast Asia, South Asia, and parts of the Middle East. Its essential oil (EO), predominantly composed of eugenol, is rich in bioactive compounds. This study aims to clarify the specific contribution of eugenol to the antioxidant, antibacterial, antifungal, and insecticidal activities of S. aromaticum EO by comparing their individual effects. Additionally, density functional theory (DFT) calculations were employed to examine the antioxidant mechanism of eugenol and its role in enhancing the overall activity of the EO.

Materials and methods

The EO was obtained from S.

SUBMITTER: Rahim N 

PROVIDER: S-EPMC11913364 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature