Antilipase activities of cultivated peppermint and rosemary essential oils: in vitro and in silico studies.

ABSTRACT:

Background/aim

The growing interest in essential oils clearly indicates the power of nature and aligns with our increasing need to find therapeutic solutions in the natural world. This study aimed to investigate the inhibitory effects of the essential oils of Mentha × piperita and Salvia rosmarinus, harvested from the Laghouat region of Algeria, against Candida rugosa lipase (CRL) and pancreatic lipase through both in vitro and in silico studies.

Materials and methods

Essential oils were extracted via hydrodistillation and analyzed using gas chromatography-mass spectrometry and spectrophotometry. Their antilipase activities were assessed using an inhibition assay, and molecular docking was performed with AutoDock Vina to explore interactions between esse

SUBMITTER: Bengana K 

PROVIDER: S-EPMC11913368 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature