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Stoma versus no stoma prior to long-course neoadjuvant therapy in rectal cancer.


ABSTRACT:

Background

Large bowel obstruction is a possible complication in patients undergoing neoadjuvant treatment for rectal cancer; however, it may be prevented by placing a pretreatment defunctioning stoma. The aim of this retrospective study was to investigate complication rates in patients with rectal cancer undergoing long-course neoadjuvant therapy, comparing those with and without a prophylactic stoma.

Methods

All patients with rectal cancer undergoing neoadjuvant therapy between 2007 and 2022 in Region Västerbotten, Sweden, were identified using the Swedish Colorectal Cancer Registry. Patients not planned for curative long-course neoadjuvant therapy and those requiring a stoma due to urgent bowel-related issues before treatment were excluded. The primary outcome was the inc

SUBMITTER: Sanden G 

PROVIDER: S-EPMC11913605 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature