Predicting mortality in heart failure: BUN/creatinine ratio in MIMIC-III.

ABSTRACT:

Aims

Heart failure is a critical health issue with high mortality rates. The blood urea nitrogen/creatinine ratio (BCR) has proven more effective at predicting outcomes in heart failure patients than individual assessments of each marker. Nevertheless, the implications of varying BCR levels for outcomes among heart failure patients remain to be fully understood. This study explores the impact of BCR on the outcomes of these patients.

Methods and results

Employing a retrospective cohort design at a single center, this study examined 1,475 heart failure patients from the Medical Information Mart for Intensive Care (MIMIC-III) database, categorized into four quartiles based on their BCR levels. We analyzed survival outcomes using Kaplan-Meier and Cox proportional hazards models

SUBMITTER: Zhu C 

PROVIDER: S-EPMC11913865 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature