Meta-analysis of [¹⁸F]FDG-PET/CT in pulmonary sarcoidosis.

ABSTRACT:

Background

18F-Fluorodeoxyglucose (FDG) PET/CT is emerging as a tool in the diagnosis and evaluation of pulmonary sarcoidosis, however, there is limited consensus regarding its diagnostic performance and prognostic value.

Method

A meta-analysis was conducted with PubMed, Science Direct, MEDLINE, Scopus, and CENTRAL databases searched up to and including September 2023. 1355 studies were screened, with seventeen (n = 708 patients) suitable based on their assessment of the diagnostic performance or prognostic value of FDG-PET/CT. Study quality was assessed using the QUADAS-2 tool. Forest plots of pooled sensitivity and specificity were generated to assess diagnostic performance. Pooled changes in SUVmax were correlated with changes in pulmonary function tests (PFT).

Results

SUBMITTER: Donnelly R 

PROVIDER: S-EPMC11913913 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature