Frailty and pituitary surgery: a systematic review.

ABSTRACT:

Background

Frailty is a state of physiological vulnerability rendering patients susceptible to adverse perioperative outcomes after neurosurgery. The effect of frailty on surgical success and complication rates in patients undergoing transsphenoidal pituitary surgery is unclear.

Methods

A systematic review of the literature was performed in accordance with the PRISMA statement. Studies that utilised validated metrics to report the effect of frailty on pituitary surgery were included.

Results

A total of 13 studies were included, comprising 124,989 patients. Frailty was exclusively assessed with cumulative deficit metrics, however there was significant heterogeneity in patient population, frailty definitions and assessment, and outcomes. Frail patients undergoing transs

SUBMITTER: Castle-Kirszbaum M 

PROVIDER: S-EPMC11913960 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature