Automated and collision-free navigation of multiple micro-objects in obstacle-dense microenvironments using optoelectronic tweezers.

ABSTRACT: Automated parallel manipulation of multiple micro-objects with optoelectronic tweezers (OET) has brought significant research interests recently. However, the parallel manipulation of multiple objects in complex obstacle-dense microenvironment using OET technology based on negative dielectrophoresis (nDEP) remain a big technical challenge. In this work, we proposed an adaptive light pattern design strategy to achieve automated parallel OET manipulation of multiple micro-objects and navigate them through obstacles to target positions with high precision and no collision. We first developed a multi-micro-object parallel manipulation OET system, capable of simultaneous image processing and microparticles path planning. To overcome microparticle collisions caused by overlapping light patterns,

SUBMITTER: Zheng L 

PROVIDER: S-EPMC11914063 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature