Prognostic value of a novel myeloid-to-lymphoid ratio biomarker in advanced gastric cancer.

ABSTRACT:

Background

Currently, immune checkpoint inhibitors (ICIs) have excellent performance in the clinical treatment of advanced gastric cancer (AGC). However, precisely selecting AGC patients who can benefit from immunotherapy is an urgent difficulty. In this study, we investigated the immunoprognostic role of myeloid-to-lymphocyte ratio (M:L) in AGC patients.

Methods

We collected information on 268 AGC patients who were hospitalized in the Department of Medical Oncology of PLA General Hospital from December 2014 to May 2021. The patients were divided into low M: L group (< 3.76) and high M:L group (≥ 3.76). Survival differences between different M: L level groups at baseline and after treatment were analyzed by methods such as Kaplan-Meier, Cox or Logistic regression model.

R

SUBMITTER: Pan Y 

PROVIDER: S-EPMC11914242 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature