Fast whole brain relaxometry with Magnetic Resonance Spin TomogrAphy in Time-domain (MR-STAT) at 3 T: a retrospective cohort study.

ABSTRACT:

Objective

To report T₁/T₂-values of normal and normal appearing brain tissues (NBTs, healthy volunteers; NABTs, patients) acquired with a whole-brain 5-minute Magnetic Resonance Spin TomogrAphy in Time-domain (MR-STAT) protocol, and to explore relaxometry behavior in a brain tumor and in a multiple sclerosis patient.

Methods

MR-STAT was acquired in 49 participants (39 patients with neurological pathologies, age range: 21-79 years) at 3 T. Mean T₁/T₂-values were computed for: normal and normal appearing grey matter (NGM/NAGM)/white matter (NWM/NAWM)/thalamus/putamen/caudate nucleus (CN)/globus pallidus (GP). Differences between sex, brain lobes, and left/right were assessed. The age-dependency of T₁/T₂-values i

SUBMITTER: Schilder MB 

PROVIDER: S-EPMC11914305 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature