Dosimetric and radiobiological evaluation of stereotactic radiosurgery using volumetric modulated arc therapy and dynamic conformal arc therapy for multiple brain metastases.

ABSTRACT: This paper presents a clinical comparison of the target dose, normal tissue complication probability (NTCP), and plan quality between volumetric modulated conformal arc therapy (VMAT) against dynamic conformal arc therapy (DCAT) techniques to facilitate clinical decision-making in multiple brain metastases (MBM) treatment. A total of 11 cases having 33 lesions were recruited at the Union Oncology Centre, Union Hospital, Hong Kong SAR. With CT images available, all plans were optimized using both HyperArc (HA) and Brainlab Elements Multiple Brain Metastases (Elements MBM). Target coverage, normal tissue sparing, and dose distribution were compared pairwise between VMAT and DCAT. Results showed that the plans generated using both techniques achieved adequate target coverage to meet up with t

SUBMITTER: Jiang CJ 

PROVIDER: S-EPMC11914692 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature