Oral microbiota related to allergy in Norwegian adults.

ABSTRACT:

Background

Oral microbiome composition has been linked to onset and progression of several localized and systemic diseases. Associations with allergy in adults have been less explored.

Objective

We sought to identify oral microbiota associated with allergy outcomes in adults using high-throughput sequencing data.

Methods

We characterized bacterial communities of gingival samples from 453 Norwegian adults (average age, 28 years) using 16S rRNA gene amplicon sequencing. We examined more than 2200 bacterial taxa in relation to self-reported current asthma, eczema, or rhinitis, and seroatopy (IgE > 0.70 kU/L). We used linear regression to determine whether overall bacterial diversity differed by each allergic outcome and analysis of composition of microbiomes with bias co

SUBMITTER: Lee M 

PROVIDER: S-EPMC11914992 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature