Characterising practice patterns of human derived, lyophilized coagulation concentrates within the trauma quality improvement program registry.

ABSTRACT:

Objectives

We seek to describe the current practice pattern use of prothrombin complex concentrate (PCC) and fibrinogen concentrate (FC) in trauma patients.

Background

Trauma-induced coagulopathy (TIC) and endotheliopathy of trauma (EOT) contribute significantly to mortality from traumatic haemorrhage. FC, and 4-factor PCC are potential treatments for EOT and TIC, respectively.

Materials and methods

We obtained data from the Trauma Quality Improvement Program (TQIP) registry and identified patients who received either PCC or FC using procedural codes. We used descriptive statistics to characterise practice patterns of these products.

Results

There were 6 714 002 total encounters within the TQIP from 2017 to 2022, of which 10 589 received PCC and 3009 received F

SUBMITTER: Rosenthal CA 

PROVIDER: S-EPMC11915717 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature