Equilibrium mechanical properties of the human uterus in tension and compression.

ABSTRACT: A successful pregnancy relies on the proper cellular, biochemical, and mechanical functions of the uterus. A comprehensive understanding of nonpregnant and pregnant uterine mechanical properties is key to understanding different obstetric and gynecological disorders such as preterm birth, placenta accreta, uterine rupture, leiomyoma, adenomyosis, and endometriosis. This study sought to characterize the macro-scale equilibrium material behaviors of the human uterus in nonpregnancy and late pregnancy under both compressive and tensile loading. Forty four human uterine specimens from 16 patients (8 nonpregnant [NP] and 8 pregnant [PG]) were tested using spherical indentation and uniaxial tension coupled with digital image correlation (DIC). A three-strain level incremental load-hold protocol

SUBMITTER: Fang S 

PROVIDER: S-EPMC11915784 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature