Prevalence and outcomes of hypocalcemia on ED arrival in traumatic patients before blood transfusions: a systematic review and meta-analysis.

ABSTRACT:

Background

Hypocalcemia represents a critical physiological disturbance in trauma-related hemorrhagic shock patients. Nonetheless, the prevalence and effects of hypocalcemia remain uncertain. This study aims to explore the prevalence of hypocalcemia before blood transfusions and its related mortality in adult patients with major traumatic injuries.

Method

We conducted a systematic search through databases, including PubMed, EMBASE, Scopus, and Web of Science, from their inception until June 30, 2024. Patients with major traumatic injuries whose serum calcium was measured upon arrival at the emergency department (ED) were included. We excluded those with prior blood transfusions, pre-clinical studies, review articles, and studies without a control group. Meta-analysis using a

SUBMITTER: Srichuachom W 

PROVIDER: S-EPMC11916158 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature