Patient preferences for triple-class-exposed relapsed or refractory multiple myeloma treatment: a discrete-choice study.

ABSTRACT:

Aims

To quantify patient preferences for attributes of novel treatments for triple-class-exposed (TCE) relapsed and/or refractory multiple myeloma (RRMM).

Methods

Using a discrete-choice experiment, we elicited preferences for 7 attributes: objective response rate (ORR), overall survival (OS), all-grade cytokine release syndrome risk, all-grade immune effector cell-associated neurotoxicity syndrome risk, serious infection risk (grade 3+), treatment administration, and initial hospitalization requirements.

Results

OS was the most important attribute (conditional relative importance [CRI] 32.0% for a 24-month increase), followed by serious infection risk (CRI 17.3% for avoiding a 60% risk), initial hospitalization requirements (CRI 15.0% for avoiding 14 days of initial

SUBMITTER: Ailawadhi S 

PROVIDER: S-EPMC11916419 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature