AIEE-driven highly sensitive fluorescent probe for Fe<sup>3+</sup> sensing in aqueous and solid phases: application in interference-free biological media.
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ABSTRACT: Herein, a novel fluorescein-based fluorescent probe FHP was systematically designed and synthesised, which exhibited aggregation-induced emission enhancement (AIEE) properties. FHP showed the maximum emission response at a wavelength (λ max) of 516 nm. Using probe FHP, convenient and cost-effective sensing of Fe3+ in solution and solid states was accomplished with notable sensitivity and selectivity. Quenching of the FHP fluorescence intensity was observed owing to the chelation between the electron-rich probe and electron-deficient Fe3+, with a detection limit of 253 nM. The FHP-Fe3+ interaction was studied using UV-visible and fluorescence spectroscopies, dynamic light scattering (DLS), 1H-NMR titration and density functional
SUBMITTER: Khalid R
PROVIDER: S-EPMC11917468 | biostudies-literature | 2025 Mar
REPOSITORIES: biostudies-literature
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