First whole-genome sequence of Triatoma sanguisuga (Le Conte, 1855), vector of Chagas disease.

ABSTRACT: Triatoma sanguisuga is the most widespread triatomine bug species in the United States. The species vectors the human parasite Trypanosoma cruzi, which causes Chagas disease. Vector-borne Chagas disease is rarely diagnosed in the United States, but T. sanguisuga has been implicated in a handful of cases. Despite its public health importance, little is known about the genomics or population genetics of T. sanguisuga. Here, we used long-read sequencing to assemble the first whole-genome sequence for T. sanguisuga using DNA extracted from 1 adult specimen from Delaware. The final size of the genome was 1.162 Gb with 77.7× coverage. The assembly consisted of 183 contigs with an N50 size of 94.97 kb. The Benchmarking Universal Single-Copy Ortholog complete score was 99.1%, suggesting a very com

SUBMITTER: Peterson JK 

PROVIDER: S-EPMC11917478 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature