Clusters and associations of adverse neonatal events with adult risk of multimorbidity: A secondary analysis of birth cohort data.

ABSTRACT:

Objective

To investigate associations between clustered adverse neonatal events and later-life multimorbidity.

Design

Secondary analysis of birth cohort data.

Setting

Prospective birth cohort study of individuals born in Britain in one week of 1970.

Population

Respondents provided data at birth (n = 17,196), age 34 (n = 11,261), age 38 (n = 9,665), age 42 (n = 9,840), and age 46 (n = 8,580).

Methods

Mixed components analysis determined included factors, 'Birthweight'; 'Neonatal cyanosis'; 'Neonatal cerebral signs'; 'Neonatal illnesses'; 'Neonatal breathing difficulties'; and 'Prolonged duration to establishment of respiratory rate at birth', within the composite adverse neonatal event score. Log-binomial regression quantified the unadjusted and covariate

SUBMITTER: John J 

PROVIDER: S-EPMC11918344 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature