Effects of temperature and environmental covariates on the dynamic transmission of hand, foot, and mouth disease in Zhejiang, China.

ABSTRACT:

Background

Studies have documented the impact of temperature on the incidence of hand, foot, and mouth disease (HFMD); however, no study has examined its impact on the transmissibility.

Methods

The longitudinal surveillance data of HFMD in Zhejiang Province during 2013-2019 were collected from National Notifiable Infectious Diseases Reporting Information System. The incidence of HFMD was represented by daily case counts, and the transmissibility was quantified as the instantaneous reproductive number ([Formula: see text]). The case time series design was applied to investigate the association between temperature and HFMD incidence at small-scale spatial patterns (i.e., townships). General additive model was further employed to analyze the effects of temperature and other dri

SUBMITTER: Wen W 

PROVIDER: S-EPMC11918438 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature