Exploring Neural Correlates between Anxiety and Inhibitory Ability: Evidence from Task-Based fNIRS.

ABSTRACT:

Background

Cognitive control impairments in anxiety disorders are thought to be associated with deficiencies in the prefrontal network. However, a precise neural explanation for these impairments is still lacking. This study seeks to compare inhibitory ability between individuals with anxiety and healthy controls, as well as to explore the neural correlates of anxiety-related inhibitory deficits within a clinical context.

Materials and methods

A total of 118 participants were recruited, including 59 patients with anxiety and 59 matched healthy controls (HCs). Anxiety and inhibitory ability were evaluated using Zung's Self-rating Anxiety Scale (SAS), the color word Stroop task, and verbal fluency task (VFT). Additionally, changes in oxyhemoglobin (Oxy-Hb) concentrations were

SUBMITTER: Wang D 

PROVIDER: S-EPMC11918997 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature