Autonomic Inertia as a Proximal Risk Marker for Moments of Perseverative Cognition in Everyday Life in Remitted Depression.

ABSTRACT: Background: Trait perseverative cognition (PC) is associated with inflexible autonomic activity and risk for depressive recurrence. However, the identification of dynamic psychophysiological markers of PC that fluctuate within individuals over time could facilitate the passive detection of moments when PC occurs in daily life. Methods: Using intensively sampled data across 1 week (3x/day) in adults with remitted major depressive disorder (rMDD) and never-depressed controls (CONs), we investigated the utility of monitoring ambulatory autonomic complexity to predict moments of PC engagement in everyday life. Autonomic complexity metrics, including the root mean square of successive difference (RMSSD), indexing vagal control, and sample entropy, indexing signal complexity, were

SUBMITTER: Zapetis SL 

PROVIDER: S-EPMC11919009 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature