Associations of Education Attainment With Postpartum Depression and the Mediating Exploration: A Mendelian Randomization Study.

ABSTRACT: Background: Many studies have explored the relationship between education and postpartum depression (PPD), with inconsistent results. Our study is to identify which education-related factors (education attainment, qualifications, cognitive performance) played the predominant role in PPD using Mendelian randomization (MR) analysis. Then, we explored the factors that may mediate the effect of education on PPD. Method: We performed two-sample multivariable Mendelian randomization (MVMR) to assess the independent impact of education-related factors on PPD. Based on the literature review, three mediating factors that may play a role in the path of education attainment and PPD were involved in mediation analysis, including childbearing age, neuroticism score, and average total hous

SUBMITTER: Wang X 

PROVIDER: S-EPMC11919117 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature