Buckberg versus Del Nido in isolated aortic valve replacement: a prospective, two-centre, randomized trial.

ABSTRACT:

Objectives

Interest in Del Nido solution is increasing in adult cardiac surgery. This study compared Del Nido with Buckberg cardioplegia in patients undergoing isolated aortic valve replacement.

Methods

A prospective, two-centre, randomized trial was conducted from July 2019 to August 2023, with adult patients undergoing first-time isolated aortic valve replacement, and were randomized to receive Buckberg (n = 159) or Del Nido (n = 152) solution. Primary end-point was Creatine Kinase and ultrasensitive Troponin T postoperative peak level.

Results

A total of 311 patients were recruited. Total cardioplegia volume was higher in Del Nido group (1000 ml vs 374.5 ml, P < 0.001). No differences were observed in peak Creatine Kinase or Troponin T levels (422 vs 407 U/L and 28

SUBMITTER: Tauron-Ferrer M 

PROVIDER: S-EPMC11919445 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature