Difference in Cow's Milk-Related Symptom Score (CoMiSS^TM) Among Presumed Healthy Infants in Indonesia and Brazil.

ABSTRACT:

Purpose

The Cow's Milk-related Symptom Score (CoMiSS) improves the recognition of cow milk allergy (CMA) symptoms. A score of ≥10 should raise awareness of CMA. The median CoMiSS in healthy European infants aged <6 months is 3. This study aimed to determine the impact of different regions on CoMiSS in healthy infants aged <12 months to evaluate regional and age-related differences.

Methods

A prospective cross-sectional study was conducted at one hospital each in Indonesia (Jakarta) and Brazil (Sergipe). CoMiSS was assessed in healthy infants aged -12 months old.

Results

In Jakarta, a total of 286 infants (50.7% boys) were included. The median (interquartile range) CoMiSS was 1.5 (0-4); the 95th percentile was 7. In Sergipe, 101 infants (60.4% boys) were included. The

SUBMITTER: Knockaert N 

PROVIDER: S-EPMC11919533 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature