Quality of life in patients with HBV infection: A systematic review and meta-analysis.

ABSTRACT:

Background & aims

Despite nearly 250 million people worldwide estimated to have chronic HBV infection, health-related quality of life (HRQOL) in HBV-related disease has not been well characterised. Here, we summarise existing data on HBV-related HRQOL and quantify summary utility values by stage of disease.

Methods

Embase, Global Health, PubMed, and Web of Science were searched for articles investigating HBV HRQOL. Meta-analyses for utility scores were pooled by stage of disease and utility instrument; meta-regression was further adjusted for the effect of current health expenditure as a percentage of gross domestic product (CHE/GDP), as a proxy of the importance of healthcare perceived by different countries.

Results

Twenty-two articles from 19 studies, comprising 10

SUBMITTER: Fu MX 

PROVIDER: S-EPMC11919624 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature