Titanium micro-particles are commonly found in soft tissues surrounding dental implants.

ABSTRACT:

Background

Dental implants are one of the most frequently used medical devices for therapeutic purposes in dentistry. Peri-implantitis is a severe, microbial biofilm-associated condition, characterized by inflammation in peri-implant soft tissues and destruction of supporting bone. It has been suggested that metal particles originating from the implant may influence the local host response to microbial biofilms.

Methods

Soft tissue biopsies were collected from implant sites with and without peri-implantitis in 21 patients. Micro Proton-induced X-ray Emission (µ-PIXE) analysis was used to localize, quantify and characterize titanium micro-particles within tissues. RNA sequencing was performed to evaluate potential associations between titanium micro-particles and gene express

SUBMITTER: Dionigi C 

PROVIDER: S-EPMC11920262 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature