Health state utilities associated with invasive pneumococcal disease, pneumonia, and recurrent acute otitis media in young children.

ABSTRACT:

Purpose

Cost-utility analyses examining the value of new vaccines for pneumococcal disease will require health state utilities as inputs. Existing utilities for pneumococcal infections in young children are limited. The purpose of this study was to estimate health state utilities associated with pneumococcal infections in young children.

Methods

Six health state vignettes depicting infections due to Streptococcus pneumoniae were drafted based on published literature and clinician interviews. To address methodological challenges in estimating utilities for temporary infections in children 0-5 years of age, several time trade-off approaches were explored in a pilot study (N = 28 participants). In the subsequent utility elicitation study conducted in the UK, health states were

SUBMITTER: Matza LS 

PROVIDER: S-EPMC11920316 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature