Correlation of factor XIII subunit A with factor XIII activity in a population of parturient women.

ABSTRACT:

Background

The role of factor XIII in acute bleeding situations is gaining more and more importance. It has previously been shown that prepartum factor XIII activity has a significant impact on postpartum blood loss. Whether factor XIII antigen behaves in a similar manner is unknown. As postpartum hemorrhage is one of the leading causes of maternal morbidity and mortality worldwide and factor XIII antigen determination might be available more readily in some centers as compared to factor XIII activity, this is an important question to answer, especially in the emergency situation of a postpartum hemorrhage.

Objective

To assess the correlation of prepartum factor XIII antigen with prepartum factor XIII activity and to evaluate the correlation between prepartum factor XIII ant

SUBMITTER: Frevert ML 

PROVIDER: S-EPMC11920330 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature