Nomogram construction for overall survival in breast angiosarcoma based on clinicopathological features: a population-based cohort study.

ABSTRACT:

Background

Breast angiosarcoma (BAS) is a rare, aggressive malignancy with a poor prognosis, often challenging to assess due to its unique biology. This study aimed to develop a nomogram to predict 3- and 5-year overall survival (OS) for BAS patients using key clinicopathological factors.

Methods

Data from 450 BAS patients diagnosed between 2000 and 2021 were extracted from SEER database. Key variables, including age, tumor size, tumor grade, and distant metastasis status, were identified through univariate and multivariate Cox regression analyses. These factors were incorporated into a nomogram for OS prediction. The model was validated internally and externally using the concordance index (C-index), calibration curves, and decision curve analysis (DCA) to assess its predic

SUBMITTER: Ding P 

PROVIDER: S-EPMC11920551 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature