Assessing and managing bone health and fracture risk in Parkinson's disease: the BONE PARK 2 protocol.

ABSTRACT:

Background

In Parkinson's disease (PD), the propensity to fall and the higher risk of osteoporosis converge yielding a high fracture risk. Updated National Osteoporosis Guideline Group (NOGG) guidance recommends that PD should trigger a risk assessment, for example using the FRAX tool, yet clinical pathways remain sub-optimal. To address this, we generated an algorithm for the assessment and management of bone health specifically in PD.

Methods

Within the Proactive and Integrated Management and Empowerment in Parkinson's Disease randomised controlled trial (PRIME-UK RCT), bone-health metrics were collected, and all participants were offered a dual X-ray absorptiometry scan. The FRAX tool was used to obtain the 10-year probability of hip and major osteoporotic fracture (MOF),

SUBMITTER: Naylor KC 

PROVIDER: S-EPMC11920699 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature